Evaluation of propofol priming in hypertensive patients for induction of general anaesthesia
Phase 4
Completed
- Conditions
- Health Condition 1: I10-I16- Hypertensive diseasesHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2023/03/050586
- Lead Sponsor
- Pt BD Sharma PGIMS Rohtak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients of age group 18-60 years of either sex with controlled hypertension (ASA 2 Blood pressure <140 / 90 mmhg taking antihypertensives medications for at least 8 weeks.) scheduled for elective surgery under general anaesthesia will be included in the study.
Exclusion Criteria
Patients with:
1)History of allergy to study medications
2)Anticipated difficult airway
3)BMI more than 30kg/m2
4)Pregnancy and lactating women
5)Who refuse to participate in study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To access hemodynamic changes in controlled hypertensive patients when propofol priming is applied before induction of general anesthesia.Timepoint: Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure will be observed at following intervals - <br/ ><br>1) Baseline <br/ ><br>2)Immediately after premedication <br/ ><br>3)Just after priming dose of propofol <br/ ><br>4) 2 mins after priming dose of propofol <br/ ><br>5) Immediately after induction of general anaesthesia <br/ ><br>6) 3 mins after induction of general anaesthesia. <br/ ><br>7) Immediately after Intubation.
- Secondary Outcome Measures
Name Time Method Any other side effects associated with propofolTimepoint: within 24 hours after administration of propofol.;To calculate the induction dose requirements of propofol with priming. <br/ ><br>Timepoint: Immediately after Induction