Wait and See Antibiotic Prescription for Acute Otitis Media: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 试验地点
- 2
- 主要终点
- Proportion of each group that filled the antibiotic prescription
研究概览
简要总结
To determine if a wait and see prescription for ear infections in childhood reduces use of antibiotics compared to an immediate prescription
详细描述
We conducted a randomized, controlled trial evaluating a consecutive series of children diagnosed with AOM during a one year period in an urban pediatric emergency department, utilizing diagnostic recommendations from contemporary evidence-based guidelines. The objectives of the study were to determine whether treatment of AOM using a "Wait and See Prescription" (WASP) significantly reduces use of antimicrobials compared with a "Standard Prescription" (SP) and to evaluate the effects of this intervention on clinical symptoms and adverse outcomes related to antibiotic use.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Months 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children between the ages of 6 months - 12 years who were diagnosed with Acute Otitis Media
排除标准
- •clinician suspicion or diagnosis of a concurrent bacterial infection
- •patient appeared "toxic" as determined by the PEM clinician
- •patient was hospitalized
- •history of compromised immunity
- •patient was treated with antimicrobials in the preceding seven days
- •either tympanic membrane was perforated
- •myringotomy tubes were present
- •uncertain access to medical care
- •primary language of the parent or guardian was neither English nor Spanish
- •prior enrollment in the study
结局指标
主要结局
Proportion of each group that filled the antibiotic prescription
次要结局
- Clinical course of the illness; side effects of medications; days of school/work missed; unscheduled medical visits