Platelet indices as a prognostic factors in critically ill children
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- To predict the prognosis of critically ill children with the help of platelet indices and to compare the platelet indices and platelet ratios with severity of illnesses
研究概览
简要总结
Children of age >1 month and <18 years admitted to the PICU, KMC, Manipal will be taken up for the study, history will be noted (present history, past history, family history)& general examination ( Anthropometry, vitals and head to toe examination, systemic examinations) will be noted. Samples sent for platelet indices on the day admission in the PICU are noted . At admission ‘Modified PRISM 3’ score will be calculated. Platelet indices were measured using an automated blood analyser, Sysmex Automated Hematology System . Platelet count , MPV , PDW , and PCT are compared with the standard normal values . The standard values for PCT , PDW and PCT are 7.5 -11 fl ,11-18% and 0.15-0.5 % respectively for study purpose . In severe prognosis of the patient repeat sample is noticed. Data will be analyzed by using statistical software SPSS version 20.0. Aim To evaluate the utility of platelet indices as prognostic indicator in critically ill children
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Month(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •All the patients admitted in the PICU from the age group of 1 month to 18 years in Kasturba medical college and Hospital, Manipal meeting criteria for critically ill child.
排除标准
- •Children with haematological diseases (leukemias, lymphoma ,inherited bone marrow disorders, idiopathic thrombocytopenia purpura ), Children on radiotherapy or chemotherapy , Children on anti platelet therapy (Eg: Aspirin ,clopidogrel) , Recent history of any platelet transfusion, History of splenectomy.
结局指标
主要结局
To predict the prognosis of critically ill children with the help of platelet indices and to compare the platelet indices and platelet ratios with severity of illnesses
时间窗: Within 24 hours of admission
次要结局
未报告次要终点
研究者
Ranga Sai Vineeth
Kasturba Medical College, Manipal