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SGS742 in Patients With Mild to Moderate Alzheimer's Disease (AD)

Phase 2
Completed
Conditions
Alzheimer's Disease
Registration Number
NCT00093951
Lead Sponsor
Saegis Pharmaceuticals
Brief Summary

The purpose of this trial is to determine the effect of a new drug, SGS742, on memory and cognition in patients with mild to moderate Alzheimer's disease.

Detailed Description

SGS742 is a GABA(B) receptor antagonist. It is an orally active drug and possesses neurochemical and psychopharmacologic features that suggest it could improve memory and cognition in humans. The primary objective of the SGS742 clinical trial will be to determine the effect of SGS742 on memory and cognition in individuals diagnosed with mild to moderate Alzheimer's disease. The duration of the study is 3 months with 5 clinic visits.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
280
Inclusion Criteria
  • 55 to 90 years of age
  • Diagnosed with mild to moderate Alzheimer's disease
  • Willing caregiver
  • In general good health
Exclusion Criteria
  • Call 1-877-MY-MEMORY and ask to be referred to a study center located near you for entry criteria information.

Prohibited Meds:

  • Alzheimer's medications (Aricept, Exelon, Remydl, Nemenda)

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (42)

Dedicated Clinical Research

🇺🇸

Sun City, Arizona, United States

Northwest NeuroSpecialists, PLLC

🇺🇸

Tucson, Arizona, United States

Clinical Trials Incorporated

🇺🇸

Little Rock, Arkansas, United States

Margolin Brain Institute

🇺🇸

Fresno, California, United States

NervePro Research

🇺🇸

Irvine, California, United States

Center for Neurologic Studies

🇺🇸

La Jolla, California, United States

Neuro Therapeutics, Inc.

🇺🇸

Pasadena, California, United States

Pacific Research Network, Inc.

🇺🇸

San Diego, California, United States

Affiliated Research Institute

🇺🇸

San Diego, California, United States

San Francisco Clinical Research Center

🇺🇸

San Francisco, California, United States

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Dedicated Clinical Research
🇺🇸Sun City, Arizona, United States
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