Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)
Phase 2
Completed
- Conditions
- Alzheimer's Disease
- Registration Number
- NCT00074529
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Brief Summary
An investigational drug (MK0677) will be studied to determine whether it helps the memory and cognition of patients with Alzheimer's Disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 512
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive function over 12 month period; safety and tolerability over 12 month period
- Secondary Outcome Measures
Name Time Method AD symptoms over a 6 month and 12 month period measured by the CIBIC + and the ADAS-Cog. over a 6 month and 12 month period
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which MK-0677 modulates growth hormone secretion in Alzheimer's patients?
How does MK-0677 compare to cholinesterase inhibitors in slowing cognitive decline in early-stage Alzheimer's?
Which biomarkers were evaluated in NCT00074529 to assess patient response to MK-0677 treatment?
What adverse events were reported in Merck's phase 2 Alzheimer's trial with MK-0677 and how were they managed?
Are there combination therapies involving MK-0677 and amyloid-beta targeting agents for Alzheimer's disease progression?