Prevention of Postspinal Hypotension After Spinal Anesthesia for Caesarian Section, the Comparison of Crystalloid and Colloid Infusions and Their Timing Via Perfusion Index and Plethysmographic Variability Index
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Complications; Anesthesia, Spinal and Epidural, in Pregnancy
- Sponsor
- Balikesir University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Number of participants in each group who develop hypotension, and correlation between hypotension and Perfusion Index (PI) and Plethysmographic Variability Index (PVI) scores
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Prevention of postspinal hypotension after spinal anesthesia for caesarian section by use of preoperative or intraoperative volume replacement. The comparison of crystalloid and colloid infusions and their timing via perfusion index and plethysmographic variability index.
Detailed Description
To Prevent hypotension fluid replacement is usually used in pregnant patients scheduled for C/S. Different types of fluids can be used in order to achieve this. Also the timing of fluid replacement is important. In the present study patients were separated into 4 groups. Each receiving a one of two fluids in different times. ( Colloid pre-load, colloid co-load, crystalloid co-load and crystalloid pre-load.) The effect of overall hemodynamics and the incidence of hypotension are evaluated. Also peripheric monitors like perfusion index and plethysmographic variability index are evaluated for correlation.
Investigators
hafize fisun demir
Assistant Professor
Balikesir University
Eligibility Criteria
Inclusion Criteria
- •pregnant 37-41 weeks
- •one fetus
- •scheduled for C/S under spinal anesthesia
- •accepting to participate
Exclusion Criteria
- •Emergency surgery
- •placenta previa
- •preeclampsia
- •cardiovascular and cerebrovascular comorbidities
- •morbid obesity (BMI\>40)
- •pregnancy weeks \<36 and \> 41
- •The use of vasoconstrictors
- •Severe Anemia ( Hb \<9 g/dl)
- •Refusal or known contraindication for spinal anesthesia
Outcomes
Primary Outcomes
Number of participants in each group who develop hypotension, and correlation between hypotension and Perfusion Index (PI) and Plethysmographic Variability Index (PVI) scores
Time Frame: Measurements will be performed at 5 minute intervals beginning 15 minutes prior to the operation, throughout the whole operation untill the end.
Hypotension is going tobe measured in mmHG in 5 minute intervals and PI and PVI measurements are also recorded at the same time intervals. A decrease in blood presssure exceeding % 20 of the preoperative basal blood pressure measurement will be recorded as hypotension. The number of patients who develop hypotension will be recorded. Statistic difference will be avaluated between groups. Hypotensive episodes are going to be comparised with the PI and PVI measurements at the same time period and evaluation for correlation will be performed.