The role of attention in endogenous pain control
- Conditions
- fibromyalgiamusclejoint or bone10028393
- Registration Number
- NL-OMON35822
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Patients will have the diagnosis of primary fibromyalgia according to the American College of Rheumatology (ACR) classification criteria. Control participants will be matched on age and educational level to fibromyalgia patients and will be healthy and pain-free as determined by a general health questionnaire, and not take any psychoactive medication or analgesics. All subjects will be adults over the age of 18 years old and speak Dutch fluently.
The inability to give informed consent, a serious neurological or psychiatric condition besides fibromyalgia, current participation in another research protocol that could interfere or influence the outcome measures of the present study , current use of sedative psychotropic or analgesic drugs (e.g., benzodiazepine, antiepileptics, barbiturates and opioids) except amitriptyline in low dosages (<50 mg/day), or when there is any serious injury to the body regions to be tested as reported by the research participant.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter is the effect of attentional modulation on CPM<br /><br>efficacy in patients with fibromyalgia compared to healthy controls. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary parameters are: 1) attentional task performance in patients with<br /><br>fibromyalgia versus healthy controls, 2) associations between CPM efficacy and<br /><br>cognitive inhibition, and 3) sex differences in CPM efficacy and attentional<br /><br>effects in fibromylagia versus healthy controls. </p><br>