Sensitivity and Specificity of Aridol Challenge for a Diagnosis of Asthma by a Specialist Pulmonologist
- Conditions
- Asthma
- Registration Number
- NCT00491153
- Lead Sponsor
- St. Olavs Hospital
- Brief Summary
The purpose of this study is to estimate the sensitivity, specificity and positive and negative predictive values of a positive Aridol challenge with respect to a specialist pulmonologist diagnosis of asthma in corticosteroid naive subjects with asthma-like symptoms and no previous diagnosis of asthma. The comparator is methacholine provocation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 35
- Informed consent
- Provisional or possible asthma diagnosis
- FEV1 at least 70% of predicted at inclusion
- Contraindications for bronchial provocation challenge or spirometry
- Respiratory tract infection within previous 6 weeks
- Significant co-morbidity
- > 10 pack year smoking history
- Other lung diseases
- Pregnancy, lactation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method sensitivity, specificity and positive and negative predictive values of a positive Aridol bronchial challenge test 1 day with respect to asthma diagnosis by a specialist pulmonary physician in corticosteroid-naïve subjects presenting with signs and symptoms suggestive of asthma but without a definitive diagnosis.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
St.Olavs Hospital, University Hospital of Trondheim
🇳🇴Trondheim, South Trøndelag, Norway
Dr Alf Magne Heggli medical practice
🇳🇴Trondheim, South Trøndelag, Norway
Haukeland University Hospital
🇳🇴Bergen, Norway