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Clinical Trials/NCT05726331
NCT05726331
Recruiting
Not Applicable

Combined Chiropractic Care and Tai Chi for Chronic Non-Specific Neck Pain

Harvard University Faculty of Medicine1 site in 1 country48 target enrollmentOctober 25, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neck Pain
Sponsor
Harvard University Faculty of Medicine
Enrollment
48
Locations
1
Primary Endpoint
Recruitment rate
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

This feasibility project aims to evaluate the effectiveness of chiropractic care combined with Tai Chi (TC) training to reduce pain and disability in adults with chronic non-specific neck pain (CNNP).

Detailed Description

This is a three-armed, mixed-methods pilot study. 48 adults with CNNP will be randomized to receive either 1) 10 chiropractic treatments (delivered over 16 weeks) with concurrent TC training (16 weeks of group training) plus enhanced usual care (EUC) with CNNP educational materials); 2) chiropractic care plus EUC; or 3) EUC alone. Individuals will be followed for 8 weeks after the end of their intervention period to assess longer-term outcomes. Our primary outcomes will be focused on the feasibility of recruiting, retaining and monitoring the safety of adults with CNNP into our trial. Secondary clinical outcomes include following patients centered-outcomes: pain, disability, health-related quality of life, self-efficacy, cognitive and affective outcomes (postural awareness, pain catastrophizing, fear of movement, interoceptive awareness).

Registry
clinicaltrials.gov
Start Date
October 25, 2023
End Date
December 31, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Harvard University Faculty of Medicine
Responsible Party
Principal Investigator
Principal Investigator

Peter Wayne

Principal Investigator

Harvard University Faculty of Medicine

Eligibility Criteria

Inclusion Criteria

  • Chronic nonspecific neck pain at least 5 days a week for at least 3 consecutive months
  • Neck pain averaged over past week of 3 or more on numerical rating scale ranging from 0 to 10, with 10 described as 'worst neck pain imaginable'
  • Neck Disability Index score of 5 or greater
  • Agreeable to participate in all study procedures and be randomized to all intervention groups
  • Fluent in English

Exclusion Criteria

  • Currently, or having received chiropractic care in past 12 months
  • Regular practice (on average, weekly) of Yoga, Tai Chi or Qigong in the past 6 months
  • Any major systemic illness or unstable medical condition (e.g. Parkinson's disease, cancer) or psychiatric condition requiring immediate treatment or that could lead to difficulty complying with the protocol
  • Any disability precluding exercise practice
  • History of stroke, carotid artery dissection, or vertebral artery dissection
  • Signs of myelopathy or carotid bruits or evidence of pathological hypermobility (e.g. Ehlers Danlos Syndrome) during the clinical exam
  • Neck pain caused by congenital deformity of the spine that contraindicate treatment, neck pain related to neoplasm, inflammatory rheumatic disease, neurological disorder, active oncologic disease, severe affective disorder, addiction, or psychosis
  • Neck pain associated with unstable radicular pain or radiculopathy
  • Pregnancy
  • Recent spinal injections (in the past 4 weeks)

Outcomes

Primary Outcomes

Recruitment rate

Time Frame: Through study completion (an average of 18 months)

Recruitment rate will be evaluated with respect to rate of enrollment, defined as randomization into the trial.

Retention rate

Time Frame: Through study completion (an average of 18 months)

Retention rate will be quantified by the proportion of subjects who remain in the study to complete the 24-week visit.

Intervention adherence

Time Frame: Through study completion (an average of 18 months)

Intervention adherence will be measured by collection of chiropractic visit attendance and Tai Chi class attendance data.

Secondary Outcomes

  • Pain intensity(Baseline, 16-weeks, and 24-weeks)
  • Pain on movement (POM)(Baseline, 16-weeks, and 24-weeks)
  • Disability(Baseline, 16-weeks, and 24-weeks)
  • Self-efficacy(Baseline, 16-weeks, and 24-weeks)
  • Postural awareness(Baseline, 16-weeks, and 24-weeks)
  • Fear of Movement(Baseline, 16-weeks, and 24-weeks)
  • Interoceptive Awareness(Baseline, 16-weeks, and 24-weeks)
  • Perceptions of treatments(Baseline and 16-weeks)
  • Bothersomeness of pain(Baseline, 16-weeks, and 24-weeks)
  • Health-related quality of life(Baseline, 16-weeks, and 24-weeks)
  • Pain Catastrophizing Scale(Baseline, 16-weeks, and 24-weeks)

Study Sites (1)

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