NCT04124718CompletedNot Applicable
Association Between Enamel Gene Variants and Dental Caries in Adults
Recep Tayyip Erdogan University Training and Research Hospital1 site in 1 country160 target enrollmentStarted: December 26, 2019Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- past caries experience
Study Overview
Brief Summary
VDR and TFIP11 Gene polymorphism and gene-environment interactions on caries etiology and susceptibility in adults.
Detailed Description
To date, genes can be grouped into categories based on the factor influencing dental caries. The major candidate gene categories to date include enamel formation genes, immune response genes, genes related to saliva, and genes related to taste and dietary habits.
TFIP11 and VDR genes are related to enamel formation genes
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 24 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •adult be between 24 and 40 years old
- •subject has DMFT (Decayed, Missing, Filled, Permanent Tooth) DMFT≤4 , or, DMFT>13.9
Exclusion Criteria
- •systemic or genetic disorders
- •orthodontic appliances
- •pregnant women
Outcomes
Primary Outcomes
past caries experience
Time Frame: 3 weeks
Each tooth will be examined and recorded as decayed, missing, or filled
Secondary Outcomes
- Plaque index(3 weeks)
Investigators
Gul Yildiz Telatar
Principal Investigator
Recep Tayyip Erdogan University Training and Research Hospital
Study Sites (1)
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