A Prospective Study on the Effectiveness and Safety Evaluation of Dual Wavelength Long-pulsed 755nm Alexandrite/1,064nm Nd:YAG for Treatment of Cutaneous Vascular Lesions

The erythema index (EI) significantly decreased on both treated sides (LPAL 366.5?±?101.0 vs. 295.8?±?90.2, p?<?0.001, PDL 369.0?±?124.3 vs. 302.7?±?92.1, p?<?0.001) 1 month after fourth treatment (visit 5). Also 3 months after the fourth treatment (visit 6), the reduction in the EI was well maintained on both sides (LPAL 360.3?±?96.8 vs. 282.0?±?89.2, p?<?0.001, PDL 364.3?±?121.6 vs. 281.6?±?97.8, p?<?0.001). When comparing the improvement in the EI between the two groups, the percentage reduction in the EI on the LPAL-treated side was not inferior to the PDL-treated side (visit 5: LPAL 18.7?±?15.7% vs. PDL 16.4?±?12.9%, p?=?0.501 and visit 6: LPAL 21.7?±?13.9% vs. PDL 21.9?±?15.2%, p?=?0.943).