Clinical evaluation of Supplementary Use of an Erythritol Powder Air Polishing Device in Non-Surgical Periodontal Therapy: Randomized Clinical Trial
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 21
研究概览
简要总结
Clinical results In both test and control groups, there was a significant decrease in PD, PI, and BOP, accompanied by an increase in REC, and significant gain in CAL, when compared between before treatment and after treatment. There was no significant difference in clinical parameter changes between the test and control groups. Clinical parameters were improved after 1 month compared to the baseline; in contrast, results at 3 months after treatment were worse than at 1 month after treatmen Microbiological results Total bacterial counts were significantly (p <0.05) changed among baseline, 1 month after treatment and 3 months after treatment, in both test and control groups. In the test group, the number of bacteria decreased significantly (p <0.05) between baseline and 1 month after treatment. In the control group, the number of bacteria increased significantly between 1 month and 3 months after treatment (p <0.05, Fig. 1). The relative expression levels of A. actinomycetemcomitans, C. rectus, E. corrodens, F. nucleatum, P. intermedia, T. denticola, and T. forsythia were not significantly different following treatment in either test or control groups. However, the relative expression level of P. gingivalis was significantly lowered between baseline and 1 month after treatment (p <0.05, Fig. 2).
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19(Year) 至 70(Year)（—）
- 性别
- All
入选标准
- •Patients were enrolled in the study if they visited the Pusan National University Dental Hospital between March 2017 and August 2017 and wanted to participate voluntarily. Inclusion criteria for this study were as follows: 1) Patients who ranged in age from 19 to 70 years old; 2) Patients with moderate chronic periodontitis, who required removal of calculus and root planing treatment; 3) Patients exhibiting at least one tooth with a probing pocket depth of 4–6 mm in any of the teeth from the incisor to the second molar on either side of the oral cavity.
排除标准
- •Exclusion criteria for this study were as follows: 1) Patients with systemic disease; 2) Patients who were pregnant or breastfeeding; 3) Patients who received periodontal treatment or antibiotic treatment within 6 months prior to participating in the study.