MedPath

ew gait rehabilitation in Parkinsonian syndrome

Phase 1
Conditions
Parkinsonian syndrome
Parkinson's disease
Registration Number
JPRN-jRCTs042190007
Lead Sponsor
eki Yoshino
Brief Summary

These findings showed that gait-combined closed-loop tES over the cerebellum improved Parkinsonian gait disturbances, possibly through the modulation of brain networks generating gait rhythms. This new non-pharmacological and non-invasive intervention could be a breakthrough in restoring gait function in patients with PD and related disorders.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
28
Inclusion Criteria

1) Parkinson's disease and Parkinsonian syndrome including PSP, CBS, DLBD, MSA, vascular parkinsonism, NPH who was diagnosed by neurologists
2) age 40-80

Exclusion Criteria

1) history of other neurological disorders
2) internal metal and clip in the skull
3) heart pacemaker
4) history of epilepsy
5) history of past operation related to orthopedic disorders
6) heart diseases such as myocardial infarction, angina, high blood pressure(BP 200/120 mmHg<) and chronic pulmonary disorders
7) internal metal which cannot confirm that it is non-magnetic bodies such as nerve stimulator, clip for aneurysms, insulin pump, stent, the metal in the eyeball
8) remarkable hearing disorder and does not get communication
9) pregnant woman
10) doctors judged inappropriate

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath