Long-Term Outcome Following Regenerative Periodontal Treatment of Intrabony Defects

Completed

• Conditions: Regenerative Periodontal Treatment
• Interventions: Procedure: regeneration treated teeth loss; Procedure: regenerated treated teeth with clinical attachment loss

• Registration Number: NCT03145246
• Lead Sponsor: Mahidol University

Brief Summary

Many years ago, periodontal regenerative treatment has been done in Periodontics and Oral Medicine Clinic, Faculty of Dentistry, Mahidol University, Bangkok, Thailand. However, there is still lacking of study about long-term result of periodontal regenerative treatment of intrabony defects.

Detailed Description

Beside, in the present, some materials for periodontal regenerative treatment are still expensive. Periodontists and patients have to plan together based on not only rationale of treatment but also cost and effectiveness. Thus the long-term result of treatment could be useful for the decision making.

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study Start: 2015-01
• Primary Completion: 2015-04
• Study Completion: 2015-04
• Study First Submitted: 2015-11-13
• Status Verified: 2017-05
• Study First Submitted QC: 2017-05-05
• Last Update Submitted: 2017-05-05
• Study First Posted: 2017-05-09
• Last Update Posted: 2017-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 89

Inclusion Criteria

• Patients who received regenerative therapy of the intrabony defects
• Patients who had the record of re-evaluation at 1 year post-surgery

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Exclusion Criteria

• Patients who received regenerative therapy involving the furcation area
• Patients who received non-periodontal regenerative therapy
• Patients who received endodontic regeneration
• Patients who had an incomplete periodontal data recording

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
tooth loss	regeneration treated teeth loss	regeneration treated teeth loss
clinical attachment loss ≥ 2 mm	regenerated treated teeth with clinical attachment loss	regenerated treated teeth with clinical attachment loss ≥ 2 mm
clinical attachment loss loss < 2 mm	regenerated treated teeth with clinical attachment loss	regenerated treated teeth with clinical attachment loss \< 2 mm

Primary Outcome Measures

Name	Time	Method
Percentage of regenerative-treated tooth loss after periodontal regeneration	1 year	Percentage of regenerative-treated tooth loss since 1 year after periodontal regeneration until last visit of supportive periodontal treatment
Percentage of regenerative-treated sites with clinical attachment loss ≥ 2 mm	1 year	Percentage of regenerative-treated sites with clinical attachment loss ≥ 2 mm since 1 year after periodontal regeneration until last visit of supportive periodontal treatment

Secondary Outcome Measures

Name	Time	Method
Variables (patient and tooth characteristics) that associated with tooth loss or clinical attachment loss	1 year	Patient variables and tooth characteristics associated with regenerative-treated tooth loss or sites with clinical attachment loss ≥ 2 mm from any supportive periodontal treatment visits (the last supportive periodontal treatment visit) compared to baseline or 1-year after surgery.