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Informed Decision Making Intervention in Screening for Prostate Cancer of Predominantly African American Participants in a Community Outreach Program

Not Applicable
Terminated
Conditions
Prostate Carcinoma
Interventions
Other: Educational Intervention
Procedure: digital rectal examination
Other: Pre-test administration
Other: Survey Administration
Other: Post test administration
Other: Prostate-specific antigen measurement
Registration Number
NCT02419846
Lead Sponsor
Case Comprehensive Cancer Center
Brief Summary

This clinical trial studies an informed decision making intervention of screening for prostate cancer in predominantly African American participants. It also evaluates participants' knowledge about prostate cancer screening and to improve understanding. Using decision aids such as culturally sensitive written material, verbal information, and videos to educate patients about screening may increase patient participation and knowledge. This may increase confidence in participants' decisions. Raising awareness about prostate cancer in the communities may increase the participants' willingness to be screened for prostate cancer once they have learned about it.

Detailed Description

PRIMARY OBJECTIVES:

(A) To assess the effectiveness of a proposed educational model for informed decision about Prostate Cancer in high risk men over age 40 which compares informed decision making and shared decision making (B) to improve knowledge about prostate cancer in men over age 18

OUTLINE:

Participants complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Some participants then undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.

After completion of study, participants are followed up periodically.

Recruitment & Eligibility

Status
TERMINATED
Sex
Male
Target Recruitment
319
Inclusion Criteria
  • Men over the age of 18 will be asked to participate in the educational component of the program; men over the age of 40 will be offered the screening component after the educational portion of the event; participants over age of 40 will have the opportunity to make an informed decision in regards to prostate cancer screening based on this information and the educational material; American Cancer Society (ACS) guidelines recommend having a discussion about screening in men who have an expected mortality of greater than 10 years; data on comorbidities and 10-year mortalities will be collected on every participant using the University of California at San Francisco (UCSF) mortality index
  • Educational component: men over the age of 18
  • Screening component: men over age 40
Exclusion Criteria
  • Known personal history of prostate cancer
  • Active malignancy, metastatic disease, or anyone undergoing treatment for malignancy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Men over 40: Screening with interventionEducational InterventionParticipants over the age of 40 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Participants may undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.
Men over 40: Screening with interventiondigital rectal examinationParticipants over the age of 40 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Participants may undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.
Men over 40: Screening with interventionPre-test administrationParticipants over the age of 40 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Participants may undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.
Men over 40: Screening with interventionSurvey AdministrationParticipants over the age of 40 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Participants may undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.
Men 18-39: Educational interventionEducational InterventionParticipants between 18 and 39 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences.
Men 18-39: Educational interventionPost test administrationParticipants between 18 and 39 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences.
Men 18-39: Educational interventionPre-test administrationParticipants between 18 and 39 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences.
Men over 40: Screening with interventionProstate-specific antigen measurementParticipants over the age of 40 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Participants may undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.
Men over 40: Screening with interventionPost test administrationParticipants over the age of 40 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences. Participants may undergo a screening exam comprising a prostate specific antigen level and digital rectal exam.
Men 18-39: Educational interventionSurvey AdministrationParticipants between 18 and 39 complete an educational intervention comprising a 10-20 minute PowerPoint presentation given by an experienced healthcare professional that discusses prostate cancer facts, screening guidelines, risks, benefits, and consequences.
Primary Outcome Measures
NameTimeMethod
Proportion of participants over age 18 that demonstrate improved knowledge about prostate cancer screeningUp to 1 year

Improved understanding will be defined as an increase in the number of correct answers seen on the post Prostate Screening Education Questionnaire. The underlying likelihood of a positive response, or improved understanding of prostate cancer screening, can be estimated using a 95% confidence interval that has a maximum half-width of 6%.

Proportion of participants over age 40 who find this education and screening model helpful in making an informed decision about prostate cancer screening as measured by the satisfaction survey questionsUp to 1 year

Helpfulness of the program will be measured on a 5-point Likert scale where the two uppermost categories are considered a positive response.

Secondary Outcome Measures
NameTimeMethod
Proportion of participants who choose screening after educational interventionUp to 1 year
Proportion of participants referred to a primary care physician who did not previously have a primary care physicianUp to 1 year
Proportion of participants who asked the physician to make a decision for them in spite of educational interventionUp to 1 year
Proportion of abnormal results found with screening and referred to follow-up assessed as per National Comprehensive Cancer Network guidelinesUp to 1 year
Proportion of participants with family history of prostate cancerUp to 1 year
Proportion of participants who choose to enter the clinical trialUp to 1 year
Proportion of participants with a high 10-year mortality based on UCSF index who choose to be screened for prostate cancer after educational interventionUp to 1 year
Proportion of participants diagnosed with malignancy based on follow up biopsies and work-up during the course of the studyUp to 1 year
Proportion of participants who expressed satisfied with this proposed informed consent and education modelUp to 1 year
10-year expected mortality based on USCF 10-year Mortality Index for all participantsUp to 1 year

Trial Locations

Locations (1)

Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center

🇺🇸

Cleveland, Ohio, United States

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