The Impact of CRT on Renal Function

Completed

• Conditions: Chronic Kidney Diseases; Chronic Heart Failure

• Registration Number: NCT04516525
• Lead Sponsor: University of Rzeszow

Brief Summary

The study is observational, prospective, including patients undergoing CRT-D / CRT-P implantation in the department of cardiology. In the current project, the researchers assumed that the improvement in cardiac function obtained in patients qualified according to the ESC / PTK guidelines for resynchronization therapy may improve renal function in a prospective 12-month follow-up. In addition, it is planned to take into account the possibility of temporary deterioration of kidney function, which may occur immediately after implantation of the resynchronization device due to the nephrotoxic effect of the contrast agent.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-15
• Primary Completion: 2018-12-15
• Status Verified: 2020-08
• Study Completion: 2020-08-06
• Study First Submitted: 2020-08-06
• Study First Submitted QC: 2020-08-15
• Last Update Submitted: 2020-08-15
• Study First Posted: 2020-08-18
• Last Update Posted: 2020-08-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

Adult patients with heart failure who had met the criteria for CRT implantation according to European Society of Cardiology guidelines for the treatment of heart failure

Exclusion Criteria

• no written consent to participate in the study
• no indications for CR implantation
• current infection
• children
• pregnant women

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of changes renal function: 48 hours, one month and one year after cardiac resynchronization therapy device implantation procedure.	1 year for each patient in the study	Assessment of the number of patients with with chronic type 2 cardio-renal syndrome with improvement or deterioration renal function assessed by blood and urine biomarkers within the first 48 hours, one month and one year after CRT implantation.