Assessment of the Impact of Resynchronization Therapy on Renal Function
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Kidney Diseases
- Sponsor
- University of Rzeszow
- Enrollment
- 74
- Primary Endpoint
- Evaluation of changes renal function: 48 hours, one month and one year after cardiac resynchronization therapy device implantation procedure.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The study is observational, prospective, including patients undergoing CRT-D / CRT-P implantation in the department of cardiology. In the current project, the researchers assumed that the improvement in cardiac function obtained in patients qualified according to the ESC / PTK guidelines for resynchronization therapy may improve renal function in a prospective 12-month follow-up. In addition, it is planned to take into account the possibility of temporary deterioration of kidney function, which may occur immediately after implantation of the resynchronization device due to the nephrotoxic effect of the contrast agent.
Investigators
Agnieszka Gala-Bladzinska
Principal Investigator
University of Rzeszow
Eligibility Criteria
Inclusion Criteria
- •Adult patients with heart failure who had met the criteria for CRT implantation according to European Society of Cardiology guidelines for the treatment of heart failure
Exclusion Criteria
- •no written consent to participate in the study
- •no indications for CR implantation
- •current infection
- •pregnant women
Outcomes
Primary Outcomes
Evaluation of changes renal function: 48 hours, one month and one year after cardiac resynchronization therapy device implantation procedure.
Time Frame: 1 year for each patient in the study
Assessment of the number of patients with with chronic type 2 cardio-renal syndrome with improvement or deterioration renal function assessed by blood and urine biomarkers within the first 48 hours, one month and one year after CRT implantation.