Immersive Virtual Reality for Neuropathic Pain

Not Applicable

Completed

• Conditions: Neuropathic Pain; Neuropathy; Complex Regional Pain Syndromes; Phantom Limb Pain
• Interventions: Other: Immersive Virtual Reality

• Registration Number: NCT03203772
• Lead Sponsor: Loma Linda University

Brief Summary

Investigating how neuropathic limb pain, including phantom limb pain or complex regional pain syndrome, is affected by virtual reality. While several studies have looked into virtual reality for treating this type of pain, few have used the latest immersive virtual reality hardware combined with motion control for an engaging virtual mirror therapy experience. The investigators are interested in studying the use of virtual reality as an alternative treatment option for these conditions.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-14
• Study First Submitted: 2017-06-05
• Study First Submitted QC: 2017-06-28
• Study First Posted: 2017-06-29
• Primary Completion: 2019-12-31
• Study Completion: 2019-12-31
• Status Verified: 2021-05
• Last Update Submitted: 2021-05-12
• Last Update Posted: 2021-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Diagnosis of complex regional pain syndrome or phantom limb pain in an upper or lower limb

Exclusion Criteria

• Cognitive impairment leading to inability to make own medical decisions
• Complete inability to utilize leg or arm muscles that are needed for motion controller tracking
• History of seizures within the last year

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Limb neuropathic conditions	Immersive Virtual Reality	Includes phantom limb pain, complex regional pain syndrome

Primary Outcome Measures

Name	Time	Method
Pain Relief with Virtual Reality Therapy: Visual Analog Scale	Change from initial scores prior to virtual reality exposure to immediately prior to and following virtual reality sessions, and up to 8 weeks following last sessions	Change in Visual Analog Pain Scale will be measured. This will be done by obtaining pain scale scores immediately prior to therapy session, immediately following therapy, and several weeks post last therapy session.
Pain Relief with Virtual Reality Therapy: Short-Form McGill Pain Scale	Change from initial scores prior to virtual reality exposure to immediately prior to and following virtual reality sessions, and up to 8 weeks following last sessions	Change in Short-Form McGill Pain Questionnaire will be measured. This will be done by obtaining pain scale scores immediately prior to therapy session, immediately following therapy, and several weeks post last therapy session.
Feasibility of Virtual Reality Environment Use Questionnaire	Immediately following final virtual reality session	Using a questionnaire, feedback over participant self-reported tolerance of the virtual reality environment, participant likelihood of recommending this therapy to others with similar conditions, reported sense of presence in presented scenario(s), comfort of virtual reality devices, impact on self-reported functional ability outside of clinic, and overall impression of virtual reality therapy will be recorded.
Pain Relief with Virtual Reality Therapy: Wong-Baker Scale	Change from initial scores prior to virtual reality exposure to immediately prior to and following virtual reality sessions, and up to 8 weeks following last sessions	Change in Wong-Baker Faces pain scale will be measured. This will be done by obtaining pain scale scores immediately prior to therapy session, immediately following therapy, and several weeks post last therapy session.

Trial Locations

Locations (1)

Loma Linda University Health, East Campus Outpatient Rehabilitation Center; 🇺🇸 Loma Linda, California, United States