NCT02180880已完成4 期
Symptom-Based Treatment for Neuropathic Pain in Spinal Cord Injured Patients, Randomized Clinical Trial
Ju Seok Ryu1 个研究点 分布在 1 个国家目标入组 63 人开始时间: 2012年11月最近更新:
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- Symptom based treatment of neuropathic pain
研究概览
简要总结
-
Neuropathic pain in spinal cord injured patients
-
Inclusion criteria
- pain intensity, visual analogue scale > 3
- a LANSS (Leeds assessment of neuropathic symptoms and signs) score of 12 and above
- aged ≥20
- Method
- Stop pain medications
- Test oxcarbazepine (150mg twice daily) and pregabalin (150mg twice daily)
- Check pain intensity (VAS score) with Baron's classification
详细描述
In the present study, pharmacologic treatment included pregabalin and oxcarbazepine.
Stop medications such as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), tramadol and anti-spastic drugs (baclofen, tizanidine) and other medications known to have effect on pain and the central nervous system prior to the study for at least 3 days.
-
Pain intensity (VAS score)
-
4 spontaneous characters
- electric
- burning
- pricking
- numbness
- evoked pain
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged than 20 years
- •Neuropathic pain symptoms : LANSS (Leeds assessment of neuropathic symptoms and signs) score of 12 and above
- •Visual analogue scale score of 3 and above
排除标准
- •No pregnancy
- •systemic disease
- •psychiatric disease
研究组 & 干预措施
Pregabalin and Oxcarbazpepine
Experimental
Pregabalin and Oxcarbazepine
干预措施: Pregabalin and Oxcarbazepine (Drug)
结局指标
主要结局
Symptom based treatment of neuropathic pain
时间窗: 2 week later
Pain intensity using Visual analogue scale (0\~100)
次要结局
未报告次要终点
研究者
Ju Seok Ryu
Assistant professor
CHA University
研究点 (1)
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