NCT06120413招募中不适用
Clinical Evaluation of 18F-LN1 PET/CT for Imaging of Nectin-4 in Urothelial Carcinomas
Sichuan Provincial People's Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2023年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Comparison of 18F-LN1 and 18F-FDG Uptake in Patients with urothelial carcinoma
研究概览
简要总结
The clinical feasibility of 18F-LN1 PET/CT will be evaluated in 30 patients with urothelial carcinoma, and the results will be compared with those of 18F-FDG.
详细描述
This study aims to evaluate the recognition efficiency of 18F-LN1 and 18F-FDG PET imaging for tumor target Nectin-4 in patients with urothelial carcinoma. The main method is to compare the results of visually interpreted PET images with histopathological results (through surgery or biopsy), which are the gold standard for final diagnosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 and above
- •No gender difference
- •Patients who have been diagnosed with, or are clinically highly suspected of, urothelial carcinomas and have had no other treatment within 3 months
排除标准
- •Hypertension that is difficult to control with medication, and systolic blood pressure exceeding 160mmHg
- •Complicated with chronic liver disease, myocardial infarction, stroke
- •Female patients who are pregnant (or attempting to become pregnant within six months), breastfeeding, or unwilling to use contraception
- •Abnormal cardiopulmonary function or mental state, unable to tolerate prone lying for 20 minutes
结局指标
主要结局
Comparison of 18F-LN1 and 18F-FDG Uptake in Patients with urothelial carcinoma
时间窗: 1 mouth
The correlation between the results of PET images and histopathological results
次要结局
未报告次要终点
研究者
Hao Wang
Associate senior physician
Sichuan Provincial People's Hospital
研究点 (1)
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