Ultrasound Guided Knee Injections in Musculoskeletal Medicine
- Conditions
- Knee Osteoarthritis
- Interventions
- Procedure: Joint line landmarkProcedure: Suprapatellar LandmarkProcedure: Joint line ultrasoundProcedure: Suprapatellar ultrasound guided
- Registration Number
- NCT03293238
- Lead Sponsor
- Andrews Research & Education Foundation
- Brief Summary
This study will compare the accuracy and patient reported outcomes between four different techniques used to perform a knee injection.
- Detailed Description
This study will compare the accuracy and patient-oriented outcomes between various techniques for intra-articular knee injections. Historically, a joint line (intercondylar) technique of injection at the medial or lateral joint line, reliant solely upon clinical palpation, has been the most popular approach among primary care and orthopedic providers. Newer approaches, making use of ultrasound visualization to accomplish access to the intercondylar recess and the anterolateral suprapatellar pouch, have gained in popularity. Because of uncertain accuracy with the traditional approach, this study is designed to determine if sonographic visualization combined with either of these two newer techniques improves accuracy and affects patient-oriented outcomes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 63
- Male or female, age 18 to 90
- Clinician determined need for intra-articular knee injection
- Radiograph confirmed grade 1-4 Kellgren Lawrence osteoarthritis scale
- Allergy to contrast dye, shellfish
- Allergy to egg product or hyaluronate
- Allergy to lidocaine
- Localized skin infection at planned site of injection
- Inability to complete follow-up phone call three months following the injection
- Viscosupplementation injection within 6 months of the current evaluation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Joint Line Landmark Joint line landmark Patients assigned to this group receive a standard medial or lateral joint line injection of Euflexxa without ultrasound guidance while sitting up. Suprapatellar Landmark Suprapatellar Landmark Patients assigned to this group receive an injection of Euflexxa while lying down into the suprapatellar pouch without ultrasound guidance. Joint Line Ultrasound Joint line ultrasound Patients assigned to this group receive a standard medial or lateral joint line injection of Euflexxa aided by ultrasound guidance while sitting up. Suprapatellar Ultrasound Guided Suprapatellar ultrasound guided Patients assigned to this group receive an injection of Euflexxa while lying down into the suprapatellar pouch aided by ultrasound guidance.
- Primary Outcome Measures
Name Time Method Number of Participants With Successful Knee Injection Procedure visit 3 (3-4 weeks after 1st injection) To assess presence or absence of contrast medium within the target knee joint as determined by a blinded radiologist. If contrast medium could be observed in the joint then the injection was considered a success.
- Secondary Outcome Measures
Name Time Method Procedural Satisfaction Score at 3 Months Post Injection 3 month follow-up appointment following 3rd injection Patient reported procedural satisfaction score on scale of 0 to 10. A score of 10 indicates high satisfaction with the procedure.
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Score Pre-Injection and 3 month follow-up appointment following 3rd injection Compare the Western Ontario and McMaster Universities Osteoarthritis Index between groups at the 3-month follow-up appointment. The scale is 0-100. Higher scores on the WOMAC indicate worse pain, stiffness, and functional limitations.
Trial Locations
- Locations (1)
Andrews Research & Education Foundation
🇺🇸Gulf Breeze, Florida, United States