Comparison of the effect of desogestrel 75 micrograms (progestogen only pills) and depot medroxyprogesterone acetate (DMPA) on bone markers in reproductive aged wome

Recruiting

• Conditions: The effect of desogestrel 75 micrograms (progestogen only pills) and depot medroxyprogesterone acetate (DMPA) on bone markers in reproductive aged women; desogestrel; progestogen only pills; depot medroxyprogesterone acetate; DMPA; bone markers; P1NP; CTX; Osteocalcin

• Registration Number: TCTR20240628006
• Lead Sponsor: Chiang Mai University, Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-06-28
• Last Update Posted: 19 August 2024
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

1. Female age 20 to 45 years old
2. Visit gynecologist clinic at Maharaj Nakorn Chiang Mai Hospital
3. Have indication to use progestin only hormone

Exclusion Criteria

1. Any medical condition that effects bone metabolism
2. Current medication that effects bone metabolism
3. 6 weeks postpartum or breastfeeding
4. History of abnormal bone mineral density (BMD)
5. History of hormonal drug use in 3 months

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone markers 3 months Procollagen type 1 extension peptide (P1NP), Osteocalcin (OC) and Carboxy-terminal collagen crosslinks (CTX)

Secondary Outcome Measures

Name	Time	Method
abnormal uterine bleeding 3 mo Call to in quire