The effect of azythromycin in the control of refractory asthma patients

Phase 2

• Conditions: Severe persistent asthma.; Severe persistent asthma; J45.5

• Registration Number: IRCT20100102002954N21
• Lead Sponsor: Shahroud University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 October 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

Patients with a diagnosis of chronic asthma by spirometric and clinical findings,
Existence of chronic asthma for at least the last six months,
Do not take any antibiotics for at least the last one month,
Conscious consent to participate in research.

Exclusion Criteria

Incidence of any asthma attack during the research period
Allergy to azythromycin or intolerance during treatment
Existence of infectious and severe respiratory diseases in at least one month

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measuring the severity of chronic asthma. Timepoint: Once a month. Method of measurement: ACQ standard questionnaire.;Maximum expiratory volume per second (FEV1). Timepoint: Once a month. Method of measurement: Micromedical spirometer.

Secondary Outcome Measures

Name	Time	Method
Measurement of expiratory nitric oxide ratio. Timepoint: Once a month. Method of measurement: Exhale nitric oxide test with Nobreath device.