The Effect of Fortifying the Spleen, Clearing heat, Activating Blood Method on Chronic Atrophic Gastritis: a Real World Study

Not Applicable

• Conditions: Chronic Atrophic Gastritis

• Registration Number: ITMCTR1900002735
• Lead Sponsor: The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Aged 18-65 years, gender without limitation;
2. The diagnosis of chronic atrophic gastritis was confirmed by gastroendoscopy and gastric mucosa histopathology;
3. TCM syndrome was confirmed by standard syndrome differentiation;
4. Hp negative was diagnosied by rapid urease assay or 13C breath test or 14C breath test within nearly 1 month;
5. Be able to normal verbal communication;
6. Auqired the informed consent and willing to be a volunteer.

Exclusion Criteria

1. Participating in other drug treatment studies within the nearly one month;
2. Combined with autoimmune gastritis (type A chronic atrophic gastritis), peptic ulcer (stage A1 -H2), reflux esophagitis, gastric polyp, hypertrophic gastritis, ulcerative colitis, history of gastrointestinal surgery and other disease;
3. Gastric mucosal high-grade intraepithelial neoplasia, gastrointestinal mucosal lesions suspected malignant transformation, gastrointestinal tumors;
4. Patients with malignant tumors undergoing surgery, radiotherapy and chemotherapy in the past 5 years;
5. Combined with serious organic diseases.Such as: heart (cardiac functionNYHIII-IV, hemodynamic unstable myocardial infarction, etc.), liver (decompensated stage of liver cirrhosis, etc.), kidney (chronic renal failure, uremia stage, etc.), lung (tuberculosis, acute attack of asthma, pulmonary infection, etc.), autoimmune system (active stage of systemic lupus erythematosus), etc.;
6. Allergic constitution or allergic to a variety of drugs;
7. With severe mental illness so as to unable to cooperate with researchers, such as schizophrenia, depression, anxiety, dementia and so on;
8. Pregnant, breast feeding women;
9. Uncooperative Investigator.

Study & Design

• Study Type: Observational study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Histopathology;

Secondary Outcome Measures

Name	Time	Method
Economic evaluation;Symptom Assessment;Gastroscopy evaluation;Anxiety and deprssion evaluation;Quality of life assessment;Syndrome efficacy evaluation;