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COMPARE THE EFFECTIVENESS OF THREE PLATELET RICH PLASMA INJECTIONS GIVEN IN KNEE IN OSTEOARTHRITIS OF KNEE AT AN INTERVAL OF 4 DAYS VS 14 DAYS

Phase 3
Conditions
Health Condition 1: M170- Bilateral primary osteoarthritis of kneeHealth Condition 2: M171- Unilateral primary osteoarthritisof knee
Registration Number
CTRI/2023/10/058623
Lead Sponsor
AIIMS Bhubaneswar
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients with Grade 2 and Grade 3 Osteoarthritis Knee

1.Patients must be within 40 years to 75 years of age.

2.Should comply with the needs of study visits.

3.Patients without grade 4 osteoarthritis in the other knee who have mild to moderate osteoarthritis (OA) of the knee (Grade 2 or 3 on the KL grading scale).

4.Be capable of giving consent and willing to give consent, and comply with study-related needs, activities, and visits.

Exclusion Criteria

1.Individuals with OA knees in grade 4

2.Patients who are either less than 40 years or more than 75 years

3.Patients who had an intra-articular injection of any medication in the past three months, such as corticosteroids or hyaluronic acid in the index knee.

4.Patients with any history of infection, trauma or surgery to the index knee .

5.Patients who have had organ transplantation, rheumatoid arthritis, another inflammatory condition, or who are already using immunosuppressive medications.

6.Female patients who intend to become pregnant, are nursing, or are currently pregnant.

7.Patients with severe psychiatric, psychological, and/or neurological abnormalities.

8.History of anticoagulant use

9.Known case of bleeding disorders

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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