comparison of the effect of the three methods of hemofiltration during CABG on kidney functio

Not Applicable

Recruiting

Conditions: : Comparing the effect of hemofiltration with modified and conventional methods during heart and lung pumping on kidney function (24-hour urine volume, glomerular filtration rate and CrCl after surgery.

Registration Number: IRCT20231011059689N1

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

patients between 35 and 60 years old
consciously able to sign a consent letter for participating in this research
a candidate for coronary artery bypass graft.
recognized by a left ventricle ejection fraction of more than 45%
recognized by a gloumeral filtarion rate between 70 and 120

Exclusion Criteria

patients recognized by a left ventricle ejection fraction of less than 45%
recent MI
a gloumeral filtration rate of less than 70 mili litrs per minute
kidney failure
serum creatinine of more than 1.3 miligrams per decilitr
emergency surgery
a history of diabetic nephropathy
a conjoint valve surgery
proteinuria

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum creatinine. Timepoint: before coronary artery bupass graft surgery - 24 hours after CABG - 72 hours after CABG. Method of measurement: Collection of venous blood sample and measurement of serum creatinine in clinical laboratory.;Creatinine clearance. Timepoint: before coronary artery bupass graft surgery - 24 hours after CABG - 72 hours after CABG. Method of measurement: calculating the amount using the quantity of serum creatinine and the formula : CrCl(ml/min) = ((140-age)lean body weight(kg))/(serum creatinine(mg/dl)72) * (0.85 if female).;Gloumeral filtration rate. Timepoint: before coronary artery bupass graft surgery - 24 hours after CABG - 72 hours after CABG. Method of measurement: Calculation of the amount based on the amount of serum creatinine and a defined constant with the help of the Cockcroft-Gallt formula : eGFR=((140-age)weightconstant)/(serum creatinine) constant = 1.23 for men and 1.04 for women.

Secondary Outcome Measures