Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD

Not Applicable

Not yet recruiting

• Conditions: End Stage Renal Disease on Dialysis

• Registration Number: NCT07014111
• Lead Sponsor: University of Illinois at Chicago

Brief Summary

Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-05-23
• Status Verified: 2025-06
• Study Start: 2025-06
• Study First Submitted QC: 2025-06-02
• Last Update Submitted: 2025-06-02
• Study First Posted: 2025-06-10
• Last Update Posted: 2025-06-10
• Primary Completion: 2027-02
• Study Completion: 2027-06

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Diagnosis of ESKD diagnosis and receiving hemodialysis for at least 3 months
• Can read and speak English
• Fatigue measured via visual analogue scale, score ≥4 over the last week
• Able to stand and walk one block
• Has a cell phone that can receive text messages

Exclusion Criteria

• Patient's nephrologist refuses for them to participate
• Unstable angina
• Unstable pulmonary disease or pulmonary symptoms that preclude participation
• Lower-extremity amputation without prosthetic (BKA, AKA) -Orthopedic or neurologic condition that would preclude walking or tensing/releasing of muscles-
• Cognitive impairment that, in the judgement of the research team, precludes trial participation
• Participation in the formative phase of the development of Fight Fatigue

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Feasibility of recruitment	Baseline to week 12	Recruitment metrics (enrolled/invited)
Feasibility of retention	Baseline to week 12	Retention in the study from baseline to week 12
Acceptability	End of study (Week 12)	Participant rating of acceptability (e.g., enjoyable, easy to understand) via Likert scale questions and open ended questions
Adherence to the study protocol	Baseline to week 12	Adherence to the intervention measured with adherence to step counts, number/duration of accesses on the study-specific website, and adherence to study procedures as evaluated with number of text messages read/sent messages read.