The Endothelial Count in Pxf

• Conditions: Pseudoexfoliation Syndrome

• Registration Number: NCT03265457
• Lead Sponsor: Assiut University

Brief Summary

Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.

Detailed Description

The corneal Endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency.

In patients with pseudoexfoliation syndrome , quantitative and qualitative morphological changes of the corneal endothelium have been demonstrated in specular and electron microscopic studies.

Specular microscopy is a non-invasive technique to access the structure and function of the corneal endothelium.

Our research question is to study Endothelial cell count in patients with pseudoexfoliation syndrome \& compare it to age matched group.

Study Timeline

• Study First Submitted: 2017-08-26
• Study First Submitted QC: 2017-08-26
• Study First Posted: 2017-08-29
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-25
• Last Update Posted: 2018-06-26
• Study Start: 2018-10-01
• Primary Completion: 2019-10-01
• Study Completion: 2020-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Patients with pseudoexfoliation syndrome

Exclusion Criteria

• Patients with previous intra ocular surgeries.
• Patients with uveitis
• Patients with fuck's endothelial dystrophy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison between endothelial cell count in patients with Pseudoexfoliation syndrome and age matched controls.	One year	The corneal Endothelial cell count in patients with pseudoexfoliation syndrome will be measured by the specular microscopy \& compared with the normal endothelial count in people at the same group