The Corneal Endothelial Cell Count in Eyes With Pseudoexfoliation Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Comparison between endothelial cell count in patients with Pseudoexfoliation syndrome and age matched controls.
研究概览
简要总结
Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.
详细描述
The corneal Endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency.
In patients with pseudoexfoliation syndrome , quantitative and qualitative morphological changes of the corneal endothelium have been demonstrated in specular and electron microscopic studies.
Specular microscopy is a non-invasive technique to access the structure and function of the corneal endothelium.
Our research question is to study Endothelial cell count in patients with pseudoexfoliation syndrome & compare it to age matched group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with pseudoexfoliation syndrome
排除标准
- •Patients with previous intra ocular surgeries.
- •Patients with uveitis
- •Patients with fuck's endothelial dystrophy
结局指标
主要结局
Comparison between endothelial cell count in patients with Pseudoexfoliation syndrome and age matched controls.
时间窗: One year
The corneal Endothelial cell count in patients with pseudoexfoliation syndrome will be measured by the specular microscopy \& compared with the normal endothelial count in people at the same group
次要结局
未报告次要终点
研究者
Amira Asem
Principal investigator
Assiut University