Corneal Endothelial Morphologic Assessment in Pediatric Cataract Surgery With IOL Implantation: Comparison of Preoperative and Early Postoperative Specular Microscopy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Congenital Cataract Surgery
- Sponsor
- Iladevi Cataract and IOL Research Center
- Enrollment
- 106
- Primary Endpoint
- Corneal endothelial morphology
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
Cataract surgery is known to cause loss of corneal endothelial cells. In adults, it is reported that anywhere between 2 to 15% loss of corneal endothelial cell density occurs following cataract surgery. However, no data is available regarding endothelial changes after cataract surgery with IOL implantation in pediatric eyes.
The aim of this study is to prospectively observe changes in endothelial cell density, coefficient of variation and hexagonality following cataract surgery with IOL implantation in pediatric eyes.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Eyes undergoing pediatric cataract surgery with IOL implantation at Iladevi Cataract \& IOL Research Center, Ahmedabad, India.
- •Children older than 4 years undergoing cataract surgery with IOL implantation were included.
Exclusion Criteria
- •Exclusion criteria were as follows: eyes with traumatic or subluxated cataract and inability to get preoperative specular. Intraoperatively, sulcus fixated IOLs, and eyes with no IOL implantation were excluded.
Outcomes
Primary Outcomes
Corneal endothelial morphology
Time Frame: preoperatively to 3 months postoperatively
Change in corneal endothelial cell density, (CD), coefficient of variation (CV) and % of hexagonality (6A) were studied from preoperatively to 3 months postoperatively
Secondary Outcomes
- Change in central corneal thickness(preoperatively to 3 months postoperatively)