Protecting the Corneal Endothelium During Cataract Surgery Using the Anterior Capsule: a Prospective Randomised Double-masked Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endothelial Cell Loss, Corneal
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
- Enrollment
- 70
- Primary Endpoint
- endothelium cell loss
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Cataract surgery is one of the most frequently performed surgical procedures worldwide. Since the introduction of phacoemulsification to remove the cataractous lens, risk and complication rates of cataract surgery decreased significantly.
The phacoemulsification technique utilizes a high-intensity ultrasound energy for the fragmentation and emulsification of the lens. One of the main complications during phacoemulsification, is damaging of the endothelium due to contact with lens fragments of the nucleus following turbulent flow of irrigating solution, resulting in corneal damage, inflammation of the endothelium and corneal edema.
In this study we want to evaluate the effect of the anterior capsule, gained by capsular rhexis, as a corneal shield during phacoemulsification on the corneal endothelium.
Investigators
Prim. Prof. Dr. Oliver Findl, MBA
Prim. Prof. Dr.
Vienna Institute for Research in Ocular Surgery
Eligibility Criteria
Inclusion Criteria
- •Age 21 and older
- •Written informed consent prior to surgery
- •Moderate to severe nuclear or mixed cataract
Exclusion Criteria
- •Corneal pathologies
- •Pregnancy
- •Patients with an increased surgical risk (i.e. patients with pseudoexfoliation syndrome, patients with the potential risk of intra-operative floppy iris syndrome)
Outcomes
Primary Outcomes
endothelium cell loss
Time Frame: 1 year
Comparison of the lost endothelium cells in both groups
Secondary Outcomes
- central corneal thickness(1 year)