Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery by Phacoemulsification
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cataract
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
- Enrollment
- 85
- Primary Endpoint
- Pachymetry
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
To study correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.
Detailed Description
Cataract surgery facilitates improved visual acuity through extraction of an opacified lens, followed by intraocular lens implantation. An average adult cornea has 2000 to 2500 cells/mm2, a count that diminishes with age with a rate of attrition of approximately 0.3% to 0.5% per year. Long-term postoperative corneal transparency depends on the morphological stability and functional integrity of the corneal endothelium. It is well established that all surgical interventions that require entry into the anterior chamber result in some damage to the corneal endothelium. Endothelial cell loss results in cell hypertrophy to maintain continuity, resulting in a change in endothelium cell density and morphology. Many studies have assessed the impact of various surgical techniques on endothelial damage and numerous studies have investigated the factors influencing endothelial cell loss after phacoemulsification. The goal of this study is to investigate the correlation of postoperative corneal edema with the reduction of endothelial corneal cell density after phacoemulsification.
Investigators
Eligibility Criteria
Inclusion Criteria
- •The presence of senile cataract with equivalent grades and a history of visual acuity regression
Exclusion Criteria
- •Patient with total white cataract
- •With history of ocular surgery
- •With other eye diseases (corneal pathology, Fuchs dystrophy, uveitis and glaucoma) or systemic diseases (diabetic disorder and dementia)
Outcomes
Primary Outcomes
Pachymetry
Time Frame: Day 1
Measurement of the thickness of the eye's cornea with a pachymeter
Secondary Outcomes
- Pachymetry after 1 month(Day 30)
- Endothelial cell density after 1 month(Day 30)
- Endothelial cell density(Day 1)