The effect of a three-days-during calories restrictive diet on unhealthy abdominal deposited fat; A study in patients who are planned for elective cholecystectomy.
Completed
- Conditions
- too much wrong fatvisceral obesity1001842410003018
- Registration Number
- NL-OMON34973
- Lead Sponsor
- Reinier de Graaf Groep
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1. Obese patients (BMI >27 Kg/m2)
2. Anyone planned for gallbladder surgery.
3. Informed consent signed by patient
4. Male and female patients aged 18 * 60 years
Exclusion Criteria
1. Unwillingness to cooperate with the study procedures
2. History of an active malignancy
3. BMI <27 Kg/m2
4. ESR >20
5. Serum albumin <30 g/l at entry of the study
6. Treatment with hypolipidemic drugs
7. Treatment with anti- inflammatory drugs (including glucocorticosteroids,
Non-steroidal anti-inflammatory drugs)
8. Diabetes (fasting blood glucose >7.1 mmol/l)
9. Use of anti-diabetic agents
10. No written informed consent
11. pregnancy
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main study parameters/endpoints: The effect of caloric restriction on (adipo)<br /><br>cytokine production. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Differences of (adipo) cytokine spectra of visceral and peripheral adipose<br /><br>tissue</p><br>