4 weeks of eating a diet less in calories and its effect on insulin-secretio
Not Applicable
- Conditions
- Health Condition 1: E663- Overweight
- Registration Number
- CTRI/2023/04/051807
- Lead Sponsor
- Christian Medical College, Vellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
BMI more than or equal 25 kg per metre square
Exclusion Criteria
Known case of Diabetes Mellitus
Any acute or chronic illness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Estimation of dropout rate and the reasons for it <br/ ><br>2. Compliance with the intervention as assessed by food diary and the factors affecting it including subjective measure of hunger and satiety <br/ ><br>3.Change in insulinogenic index and disposition index measured during the mixed meal challenge test <br/ ><br>Timepoint: 4 weeks
- Secondary Outcome Measures
Name Time Method â?¢Change in body weight <br/ ><br>â?¢Change in the waist and hip circumference <br/ ><br>â?¢Change in SAT and VAT mass measured through DEXA <br/ ><br>â?¢Change in HOMA-IR and HOMA-B measured from fasting glucose and insulin <br/ ><br>â?¢Change in Matsuda index measured during mixed meal challenge test <br/ ><br>â?¢Change in serum triglyceride level <br/ ><br>Timepoint: 4 weeks