Comparing pain relief with continuous pain killer infusion for 24 hours given through tubes placed in abdominal wall and continuous pain killer infusion given through tube placed in lower back region following abdominal surgery

Phase 3

Not yet recruiting

• Conditions: All patients more than 18 years planned for elective abdominal surgery will be included

• Registration Number: CTRI/2018/08/015412
• Lead Sponsor: JIPMER

Brief Summary

Post-operative pain management after surgery remains challenging for very surgeon. Studies have shown that 86% of post operative patients have moderate to extreme pain after surgery.

Epidural analgesia is a commonly used method for post operative pain management in abdominal surgery. In addition to pain relief, epidural analgesia also has some beneficial effects like reduction in pest operative ileus and surgical stress response. But it is associated with complications like hypotension events, oliguria, risk of central nervous system and systemic infections, dural puncture or epidural hematoma.

Teansversus abdominis plane block is increasingly used for pain relief following abdominal surgeries. It also has some beneficial effects on post-operative paralytic ileus. TAP block is relatively easy to perform, safe, unlike epidural analgesia, and can be performed even in patients who are on anti-coagulation therapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-09
• Last Update Posted: 2018-08-17

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

patients more than 18 years Elective Open abdominal surgeries American society of anesthesiologists (ASA) I, II and III.

Exclusion Criteria

Allergy to local anesthetist Pregnancy Patients on anti-coagulants Patients on Pre-op opiods usage Patients who do not comprehend VAS.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain relief by Visual Analogue Scale Score( Scale 0-10)	6 hours, 12 hours and 24 hours post op.

Secondary Outcome Measures

Name	Time	Method
Total leukocyte count, Interleukin-6, C- reactive protein measurement	preoperative, immediate post op and 24 hours post operative period

Trial Locations

Locations (1)

JIPMER; 🇮🇳 Pondicherry, PONDICHERRY, India

JIPMER

🇮🇳Pondicherry, PONDICHERRY, India

Dr Mamidala Srinivas

Principal investigator

9655666749

drcnu93996@gmail.com