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临床试验/NCT04451694
NCT04451694Unknown不适用

Nutritional Follow up After Hospital Discharge for Coronavirus Disease-19

Central Hospital, Nancy, France1 个研究点 分布在 1 个国家目标入组 800 人开始时间: 2020年4月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
800
试验地点
1
主要终点
nutritional evaluation

研究概览

简要总结

Coronavirus infection is responsible for muscle wasting (sarcopenia), especially during prolonged stays in intensive care. Sarcopenia, in its functional aspect also seems major in patients hospitalized for this infection, in non-ICU unit. Weight loss also appears to be significant, despite a prevalence of overweight and obesity in severe forms. Undernutrition in the obese patient is also possible (undernourished obese and sarcopenia obesity). Anosmia and dysgeusia participate in undernutrition by reducing energy intake. The rehabilitation of these patients requires nutritional support (increased protein intake) associated with progressive retraining to physical activity.

An early and proactive management procedure within Coronavirus disease-19 units has been implemented in conjunction with the Transversal Nutrition Unit (TNU). This nutritional care must be continued after discharge. Follow-up by teleconsultation or telephone consultation is put in place after the patient's discharge Primary Objective: Evaluation of nutritional status at the time of admission and discharge and home follow-up in outgoing patients from Coronavirus disease-19 Units Secondary objectives: Description of the evolution of food intake, diversity of food and coverage of needs Evaluation of the muscular strength of the wrist (by grip test in hospital) and on the arms and legs after return home (visual analog scale) Evolution of anosmia and dysgeusia (at the time of hospital admission, at the time of hospital discharge and at home) Level of physical training before infection (IPAQ) Description of the general state of health measured by the performance index - world health organization scale Description of nutritional prescriptions Description of the prevention measures and incidence of Inappropriate Refeeding Syndrome (IRS) Care needs assessments

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
16 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Covid positive (RT-PCR)

排除标准

  • Unable to answer questions by telephone or teleconsultation directly or through a relative, minors under 16 years of age

结局指标

主要结局

nutritional evaluation

时间窗: before Covid, at at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge

BMI

次要结局

  • muscle strenght(between 7 and 45 days after discharge)
  • food intake(between 7 and 45 days after discharge)
  • biological nutritional status(at the time of hospital admission, at the time of hospital discharge)
  • anosmia(at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge)

研究者

发起方
Central Hospital, Nancy, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

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