to find the effectiveness of giving intravenous fluid as precaution on improving dehydration, decreasing treatment complications, and improving treatment completion rates in patients undergoing simultaneous chemotherapy and radiation therapy for head and neck cancer.

Phase 2

• Conditions: Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

• Registration Number: CTRI/2023/10/058708
• Lead Sponsor: Christian Medical College Vellore

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients receiving chemo-radiation therapy for head and neck cancers with curative intent.

Exclusion Criteria

Medical comorbidities like chronic kidney disease or congestive heart failure where fluid supplementation should be carefully done.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Completion of 5 or more cycles of concurrent chemoradiotherapy with no or less than 3 days of break. <br/ ><br>Timepoint: Weekly assessment during the course of RT

Secondary Outcome Measures

Name	Time	Method
a) Incidence of grade 3 radiation mucositis <br/ ><br>b) Time to onset of grade 3 radiation mucositis <br/ ><br>c) Duration of grade 3 radiation mucositis <br/ ><br>d) Requirement of NG/FG tube placement after initiation of treatment e) Incidence of radiation breaks of > 3 days due to morbidity <br/ ><br>f) Incidence of unplanned hospital admissionsTimepoint: Weekly assessment during the course of RT