ASSESSMENT of FRAILTY AS a PROGNOSTIC FACTOR for MORTALITY, DISABILITY, and QUALITY of LIFE AFTER ICU ADMISSION
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 246
- 主要终点
- MORTALITY
研究概览
简要总结
Between 30% and 40% of elderly patients (over 70 years old) who require hospitalization and treatment in Intensive Care Units (ICU) exhibit a state of frailty. This condition is associated with adverse prognostic factors such as increased in-hospital mortality, functional decline, and a deterioration in their long-term quality of life. Some frail elderly patients may require invasive mechanical ventilation (ventilator) as life support during the acute phase, which has also been linked to adverse prognostic outcomes. Additionally, frailty is common in patients with severe infections, with a high mortality rate, subsequent functional decline, and reduced quality of life following ICU admission.
详细描述
This project focuses on evaluating the role of geriatric frailty (FG) as a crucial predictive factor in various clinical aspects of elderly patients requiring admission to intensive care units (ICUs). Below is a breakdown of the project's main objectives for clarity:
Frailty as a predictor of mortality:
Assess whether frailty is an independent marker that predicts mortality over different timeframes (short, medium, and long term) in elderly patients admitted to the ICU.
Frailty and functional disability:
Determine whether frailty is associated with the evolution of functional disability in the short, medium, and long term following ICU admission.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Patients with an ICU stay of less than 72 hours.
- •Patients with treatment limitations upon ICU admission, although an isolated "Do Not Resuscitate" (DNR) order is acceptable; life expectancy of less than 6 months.
- •Absence of family members or caregivers available to provide medical history. Language barriers (non-Spanish speakers without access to medical translators).
- •Structural neurological diseases requiring ICU admission, including stroke or spinal cord pathology.
- •Patients for whom 12-month follow-up is anticipated to be unfeasible.
- •Patients without consent authorization.
结局指标
主要结局
MORTALITY
时间窗: ONE YEAR
Determine whether frailty is a predictor of short-, medium-, and long-term mortality in elderly patients requiring ICU admission.
次要结局
未报告次要终点