Frailty and Post-operative Complications in Older Surgical Patients: The Implication of Frailty and Preoperative Risk Assessment - A Retrospective Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25,000
- 试验地点
- 1
- 主要终点
- Postoperative complications
研究概览
简要总结
Frailty is prevalent in older adults and may be a better predictor of post-operative morbidity and mortality than chronological age. Preoperative risk factors and physiological reserves were assessed on patients more than 70 years old who are scheduled for surgery under general or regional anesthesia. The aim of this retrospective analysis was to examine the impact of relevant geriatric assessments on adverse outcomes in older surgical patients.
详细描述
The goal of this study is to analyze the effect of frailty status on postoperative outcomes. These include postoperative complications (only ICD-10 coded diagnoses), length of hospitalization (ward/ICU), disposition, and survival. The project will also attempt to find synergism between a positive frailty status and common medical conditions (e.g. diabetes, congestive heart failure, coronary artery disease, dementia, and kidney disease), as well as anesthesiological and surgical processes (e.g. duration and type of anesthesia, surgical risk, and surgical discipline). Different assessment tools will be analyzed regarding their predictive power and clinical practicability. This should help improve preoperative risk assessment and allow for the multidimensional (physical, cognitive, social) identification of relevant frailty characteristics in the perioperative setting. All outcome parameters, including admission and discharge periods, will be collected using coded information from our hospital database. There will be no follow-up measurements after hospital discharge.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 70 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female patients with age 70 years and above scheduled for surgery in the Department of Anesthesiology and Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin
排除标准
- 未提供
结局指标
主要结局
Postoperative complications
时间窗: 06/2016-12/2022
ICD-10 coded diagnoses for the hospitalization
次要结局
- Morbidity(06/2016-12/2022)
- Intensive care unit scores(06/2016-12/2022)
- Mortality(06/2016-12/2022)
- Ventilation(06/2016-12/2022)
- Procedures(06/2016-12/2022)
- Nutritional therapy 2(06/2016-12/2022)
- Duration of Hospital stay(06/2016-12/2022)
- Duration of Intensive Care Unit Stay(06/2016-12/2022)
- Requirements for intensive care unit(06/2016-12/2022)
- Nutritional therapy 1(06/2016-12/2022)
- Disease severity(06/2016-12/2022)
- Postoperative Delirium(06/2016-12/2022)
- Medical costs(06/2016-12/2022)
- Physiotherapy(06/2016-12/2022)
- Post - intensive care syndrome(06/2016-12/2022)
研究者
Claudia Spies
Clinical director of the Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK)
Charite University, Berlin, Germany
