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临床试验/NCT03382054
NCT03382054已完成不适用

Frailty and Post-operative Complications in Older Surgical Patients: The Implication of Frailty and Preoperative Risk Assessment - A Retrospective Analysis

Charite University, Berlin, Germany1 个研究点 分布在 1 个国家目标入组 25,000 人开始时间: 2016年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
25,000
试验地点
1
主要终点
Postoperative complications

研究概览

简要总结

Frailty is prevalent in older adults and may be a better predictor of post-operative morbidity and mortality than chronological age. Preoperative risk factors and physiological reserves were assessed on patients more than 70 years old who are scheduled for surgery under general or regional anesthesia. The aim of this retrospective analysis was to examine the impact of relevant geriatric assessments on adverse outcomes in older surgical patients.

详细描述

The goal of this study is to analyze the effect of frailty status on postoperative outcomes. These include postoperative complications (only ICD-10 coded diagnoses), length of hospitalization (ward/ICU), disposition, and survival. The project will also attempt to find synergism between a positive frailty status and common medical conditions (e.g. diabetes, congestive heart failure, coronary artery disease, dementia, and kidney disease), as well as anesthesiological and surgical processes (e.g. duration and type of anesthesia, surgical risk, and surgical discipline). Different assessment tools will be analyzed regarding their predictive power and clinical practicability. This should help improve preoperative risk assessment and allow for the multidimensional (physical, cognitive, social) identification of relevant frailty characteristics in the perioperative setting. All outcome parameters, including admission and discharge periods, will be collected using coded information from our hospital database. There will be no follow-up measurements after hospital discharge.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
70 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Male and female patients with age 70 years and above scheduled for surgery in the Department of Anesthesiology and Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin

排除标准

  • 未提供

结局指标

主要结局

Postoperative complications

时间窗: 06/2016-12/2022

ICD-10 coded diagnoses for the hospitalization

次要结局

  • Morbidity(06/2016-12/2022)
  • Intensive care unit scores(06/2016-12/2022)
  • Mortality(06/2016-12/2022)
  • Ventilation(06/2016-12/2022)
  • Procedures(06/2016-12/2022)
  • Nutritional therapy 2(06/2016-12/2022)
  • Duration of Hospital stay(06/2016-12/2022)
  • Duration of Intensive Care Unit Stay(06/2016-12/2022)
  • Requirements for intensive care unit(06/2016-12/2022)
  • Nutritional therapy 1(06/2016-12/2022)
  • Disease severity(06/2016-12/2022)
  • Postoperative Delirium(06/2016-12/2022)
  • Medical costs(06/2016-12/2022)
  • Physiotherapy(06/2016-12/2022)
  • Post - intensive care syndrome(06/2016-12/2022)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Claudia Spies

Clinical director of the Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK)

Charite University, Berlin, Germany

研究点 (1)

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