Frailty and Post-operative Complications in Older Surgical Patients: The Implication of Frailty and Preoperative Risk Assessment - A Retrospective Analysis
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Frailty
- Sponsor
- Charite University, Berlin, Germany
- Enrollment
- 25000
- Locations
- 1
- Primary Endpoint
- Postoperative complications
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Frailty is prevalent in older adults and may be a better predictor of post-operative morbidity and mortality than chronological age. Preoperative risk factors and physiological reserves were assessed on patients more than 70 years old who are scheduled for surgery under general or regional anesthesia. The aim of this retrospective analysis was to examine the impact of relevant geriatric assessments on adverse outcomes in older surgical patients.
Detailed Description
The goal of this study is to analyze the effect of frailty status on postoperative outcomes. These include postoperative complications (only ICD-10 coded diagnoses), length of hospitalization (ward/ICU), disposition, and survival. The project will also attempt to find synergism between a positive frailty status and common medical conditions (e.g. diabetes, congestive heart failure, coronary artery disease, dementia, and kidney disease), as well as anesthesiological and surgical processes (e.g. duration and type of anesthesia, surgical risk, and surgical discipline). Different assessment tools will be analyzed regarding their predictive power and clinical practicability. This should help improve preoperative risk assessment and allow for the multidimensional (physical, cognitive, social) identification of relevant frailty characteristics in the perioperative setting. All outcome parameters, including admission and discharge periods, will be collected using coded information from our hospital database. There will be no follow-up measurements after hospital discharge.
Investigators
Claudia Spies
Clinical director of the Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK)
Charite University, Berlin, Germany
Eligibility Criteria
Inclusion Criteria
- •Male and female patients with age 70 years and above scheduled for surgery in the Department of Anesthesiology and Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Postoperative complications
Time Frame: 06/2016-12/2022
ICD-10 coded diagnoses for the hospitalization
Secondary Outcomes
- Morbidity(06/2016-12/2022)
- Intensive care unit scores(06/2016-12/2022)
- Mortality(06/2016-12/2022)
- Ventilation(06/2016-12/2022)
- Procedures(06/2016-12/2022)
- Nutritional therapy 2(06/2016-12/2022)
- Duration of Hospital stay(06/2016-12/2022)
- Duration of Intensive Care Unit Stay(06/2016-12/2022)
- Requirements for intensive care unit(06/2016-12/2022)
- Nutritional therapy 1(06/2016-12/2022)
- Disease severity(06/2016-12/2022)
- Postoperative Delirium(06/2016-12/2022)
- Medical costs(06/2016-12/2022)
- Physiotherapy(06/2016-12/2022)
- Post - intensive care syndrome(06/2016-12/2022)