Perioperative Frailty and Postoperative Complications: a Prospective Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Frailty
- Sponsor
- Dr. Negrin University Hospital
- Enrollment
- 138
- Locations
- 1
- Primary Endpoint
- Prevalence of frailty
- Status
- Recruiting
- Last Updated
- 8 months ago
Overview
Brief Summary
The presence of frailty is associated with a high risk of complications in the perioperative period, increasing morbidity and mortality, hospital stay, and loss of quality of life. In this prospective observational study, an evaluation of frailty was performed in patients older than 65 years old who undergo scheduled and urgent surgery. 138 patients are being included. The main objective is to evaluate the prevalence of frailty in patients older than 65 years undergoing surgery in our hospital and its association with postoperative mortality.
Detailed Description
The presence of frailty is associated with a high risk of complications in the perioperative period, increasing morbidity and mortality, hospital stay, and loss of quality of life. This is a prospective observational study in which an evaluation of frailty was performed in patients older than 65 years old who undergo scheduled and urgent surgery, including 138 patients. The main objective is to evaluate the prevalence of frailty in patients older than 65 years undergoing surgery and its association with postoperative mortality. The secondary objectives were the following: to assess the association between frailty and increased days of hospital stay, hospital readmission, and unexpected admission to ICU areas; to assess whether patients with greater frailty suffer a greater loss of postoperative functional independence; to evaluate type and frequency of complications; and to evaluate which scale is most useful to implement in the perioperative setting (Frailty Clinical Scale, Edmonton frailty test, Barthel Index, Mini-mental test, Charlson Index). Considering that the estimated percentage of frailty is 10%, with a 95% confidence interval and a 5% error margin, 138 patients are needed to accurately estimate the prevalence of frailty in the population.
Investigators
Ángel Becerra-Bolaños, MD PhD
Principal Investigator
Dr. Negrin University Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients over 65 years old undergoing urgent or scheduled surgery
Exclusion Criteria
- •Language barrier
- •Cognitive impairment or inability to assist in clinical assessment during the study
- •Refusal to participate in the study
Outcomes
Primary Outcomes
Prevalence of frailty
Time Frame: First preoperative day
Prevalence of frailty in patients older than 65 years undergoing surgery in our hospital
Postoperative complications
Time Frame: 90 postoperative days
Relationship of preoperative frailty in patients older than 65 years undergoing surgery in our hospital and postoperative mortality
Secondary Outcomes
- Functional independence(First postoperative year)
- Postoperative evolution(90 postoperative days)