Evaluation of Prognostic Monitoring for Women Who Have Completed Standard Treatment for Breast Cancer Via Analysis of Immunoinflammation-related Protein Complexes in Blood
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- immune inflammation-related protein complexes
研究概览
简要总结
The relationship between immune inflammation-related protein complexes in blood and recurrence or metastasis of breast cancer will be studied.
详细描述
200 patients with breast cancer will be followed up. Peripheral venous blood was collected every 3 to 6 months. Change regularity of breast cancer-specific immune inflammation-related protein complexes in blood at different follow-up time points will be studied. The relationship between disease-specific protein complexes and pathological state of patients will be analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 60 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Postoperative pathology confirmed invasive breast cancer after surgery for breast tumors
- •Breast cancer-related chemotherapy and radiotherapy completed
- •axillary lymph node metastasis ≥ 4
- •age ≤ 60 years old
排除标准
- •Aged above 60
- •Breast Carcinoma in situ
- •Women in pregnancy or breastfeeding
- •Suffering from other malignant tumors
- •Non-compliant patient
结局指标
主要结局
immune inflammation-related protein complexes
时间窗: 2 years
The change of immune inflammation-related protein complexes which is measured by gel permeation chromatography.
blood markers
时间窗: 2 years
The expression of CA153, CEA, CA125 in the blood of the patients, which are measured by electro-chemiluminescence immunoassay.
次要结局
未报告次要终点
研究者
Yali XU
Principal Investigator
Peking Union Medical College Hospital