Establishment of a Feasibility Model for Predicting Natural Orifice Specimen Extraction Surgery (NOSES) Based on Machine Learning.

Sixth Affiliated Hospital, Sun Yat-sen University1 site in 1 country460 target enrollmentJune 1, 2023

ConditionsMachine Learning Surgery Rectosigmoid Cancer Natural Orifice Specimen Extraction Surgery

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Machine Learning
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University
Enrollment: 460
Locations: 1
Primary Endpoint: The number of successful operations performed
Status: Not yet recruiting
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this observational study is to test in patients with resectable rectosigmoid cancers. The main question it aims to answer is establishment of a feasibility model for predicting natural orifice specimen extraction surgery (NOSES) based on machine learning.

Registry

clinicaltrials.gov

Start Date

June 1, 2023

End Date

June 1, 2026

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Sixth Affiliated Hospital, Sun Yat-sen University

Responsible Party

Principal Investigator

Yanxin Luo,MD

Principal Investigator

Sixth Affiliated Hospital, Sun Yat-sen University

Eligibility Criteria

Inclusion Criteria

•Patients diagnosed with colorectal cancer or large adenoma who are suitable for laparoscopic colorectal surgery;
•Tumor staging ≤ T3 without invasion of surrounding organs;
•No abdominal seeding or distant organ metastasis;
•Clear and complete imaging data (CT, pelvic MRI) that can be processed by a computer;
•Feasible evaluation and determination for obtaining specimens through the rectal channel during preoperative and intraoperative assessments.

Exclusion Criteria

•Contraindications for laparoscopic colorectal surgery;
•Tumor staging is T4, or there are cancer nodules;
•Presence of metastasis or distant organ metastasis;
•Incomplete imaging data;
•Preoperative intestinal obstruction;
•Tumor or specimen diameter larger than the transverse diameter of the pelvic outlet;
•Previous rectal radiotherapy;
•Unsuitable evaluation and determination for obtaining specimens through the rectal channel during preoperative and intraoperative assessments.