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Clinical Trials/NCT01883063
NCT01883063
Terminated
Not Applicable

PATIENT OUTCOME COMPARISON OF INTRAMEDULLARY LOCKED NAILING VERSUS NONOPERATIVE MANAGEMENT OF EXTRA-ARTICULAR AND MINIMALLY DISPLACED INTRA-ARTICULAR DISTAL RADIUS FRACTURES IN THE ELDERLY

Sonoma Orthopedic Products, Inc.3 sites in 1 country9 target enrollmentJuly 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Minimally Displaced Intra-articular Distal Radius Fracture
Sponsor
Sonoma Orthopedic Products, Inc.
Enrollment
9
Locations
3
Primary Endpoint
Change in Composite Patient Outcomes Over Time
Status
Terminated
Last Updated
11 years ago

Overview

Brief Summary

This is a prospective multi-site study. Subjects with distal radius fractures will be enrolled. Subjects will be treated surgically with a Sonoma WRx™ device or managed non-operatively with a splint or cast. Subjects will be enrolled in each group according to physician's standard of care (either casting/splinting or surgery) for distal radius fractures. Subjects will be enrolled based on the study's inclusion/exclusion criteria with a final qualifying decision made by a group of three independent adjudicators. The final qualifying review should allow for similar patient groups within each arm of the study due to the variability that can arise in fracture classification. Review by the adjudicators should be completed within 1 week.

Registry
clinicaltrials.gov
Start Date
July 2013
End Date
December 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sonoma Orthopedic Products, Inc.
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Closed extra-articular distal radius fracture or a minimally displaced intra-articular fracture
  • Fracture classified as an AO/OTA A2, A3, C1 or C2 with or without an ulnar styloid fracture
  • Must be treated within the first 14 days of injury,
  • Male or female greater than or equal to 65 years of age.
  • Able to understand the requirements of the study, provide a written informed consent and comply with the study protocol
  • Ability to understand and provide written authorization for use and disclosure of personal health information
  • Fracture that can be treated closed with or without closed reduction

Exclusion Criteria

  • Concomitant contralateral or ipsilateral upper extremity fractures
  • Ipsilateral ulna (excluding styloid) fracture
  • Open fracture
  • Previous ipsilateral distal radius fracture in the 2 years prior to enrollment with deformity
  • Unstable distal radioulnar joint after fracture fixation
  • Fractures where the transverse fracture line is less than 10mm from the distal radius joint surface
  • Artery or Nerve injury secondary to fracture
  • History of alcoholism
  • Currently on chemotherapy or radiation therapy
  • Currently on worker's compensation

Outcomes

Primary Outcomes

Change in Composite Patient Outcomes Over Time

Time Frame: Data will be collected at 2, 6, 12, 26, 52 weeks

Patient outcomes will be measured with the DASH, PRWE and a patient questionnaire.

Secondary Outcomes

  • Change in Composite Functional Outcomes Over Time(Data will be collected at 2, 6, 12, 26, 52 weeks)

Study Sites (3)

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