Mechanocardiography in Patients With STEMI

Active, not recruiting

• Conditions: Myocardial Infarction, Acute
• Interventions: Diagnostic Test: Mechanocardiography

• Registration Number: NCT03441724
• Lead Sponsor: University of Turku

Brief Summary

The study aim is to evaluate the capability of mechanocardiography in detecting acute myocardial ischemia in patients suffering evolving ST-segment elevation infarction.

Detailed Description

Subsequent patients with ST-segment elevation assigned to the Turku University Hospital Heart Center cathlab for primary percutaneous coronary intervention are enrolled in the study. A 2 to 15 minutes mechanocardiographic recording is acquired before the intervention. A control recording is collected after the coronary intervention, within 24 hours. These recordings are compared and the results analyzed to determine the ability of this novel modality to discriminate between the two circumstances.

Study Timeline

• Study Start: 2018-01-01
• Study First Submitted: 2018-02-07
• Study First Submitted QC: 2018-02-14
• Study First Posted: 2018-02-22
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-07
• Last Update Posted: 2024-05-08
• Primary Completion: 2025-04-01
• Study Completion: 2025-04-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Myocardial ischemia with ST-segment elevation in ECG
• Primary PCI procedure

Exclusion Criteria

• Age >17 years
• No informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
STEMI before PCI	Mechanocardiography	ST-segment elevation, recording acquired before coronary intervention
STEMI after PCI	Mechanocardiography	ST-segment elevation, recording acquired from the same patients after coronary intervention

Primary Outcome Measures

Name	Time	Method
Observed difference in mechanocardiographic signal	24 hours	In this novel method for recording cardiac mechanics, we anticipate to observe a difference in machanocardiography signal between the two states - before and after an occlusion of a coronary artery. As of yet, the precise nature of the signal change is unclear and will be clarified as the recorded signals are analyzed.

Trial Locations

Locations (1)

Turku University Hospital; 🇫🇮 Turku, Finland