Multivariate Analysis of Cough After Uniport Video-assisted Thoracoscopic Surgery Pneumonectomy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- The mean Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC) score before and after surgery
研究概览
简要总结
To explore the related factors of cough after Uniport video-assisted thoracoscopic surgery pneumonectomy, and to provide theoretical basis and social accumulation of new knowledge for the diagnosis and treatment of cough after pneumonectomy in the future.
详细描述
Intractable cough after thoracoscopic pneumonectomy is one of the common complications after pneumonectomy. The incidence of cough can reach 25% ≤ 50%. Cough after operation can aggravate the pain of incision, prolong the hospitalization time, increase the cost of hospitalization, affect the conversation and even sleep of the patients, increase the psychological burden of the patients, and reduce the quality of life of the patients accordingly. Therefore, through this study, the investigators hope to understand the related factors of cough after thoracoscopic pneumonectomy and whether there are predictable risk factors, so as to provide theoretical basis for reducing the occurrence of cough after pneumonectomy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years old, male and female
- •Uniport video-assisted thoracoscopic surgery
- •No cough symptoms within two weeks before operation
- •Informed consent form was signed before operation
排除标准
- •Diabetes , heart, brain, liver and kidney diseases
- •Chest radiographs / CT in recent months indicate pneumonia
- •Pulmonary function cannot tolerate lobectomy / segmental / cuneiform resection
- •Distant metastasis patients
- •Before operation, there were internal causes of cough (including respiratory tract infectious diseases, pharyngitis, allergic rhinitis, posterior nasal drip syndrome, etc.)
结局指标
主要结局
The mean Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC) score before and after surgery
时间窗: The day before surgery,two weeks after surgery,one month after surgery
The Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC), which assesses the cough-related quality of life, consists of 19 items divided into three domains: the physical (8 items), psychological (7 items) and social (4 items) domains. A 7-point Likert scale was used to score individual domains. The total scores ranged from 3 to 21, with a higher score indicative of a better health status
次要结局
- Hospitalization days(From the first days after surgery to discharge,up to 4 weeks)
- Drainage(Measure the volume every 24 hours,up to 4 weeks)
- Anesthesia time(Record total anesthesia during surgery)