NCT04958005已完成不适用
Evaluation of Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children With Early Childhood Caries.
Aydin Adnan Menderes University1 个研究点 分布在 1 个国家目标入组 58 人开始时间: 2021年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- IL-32
研究概览
简要总结
This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.
详细描述
Fifty six children ( 28 with early childhood caries and 28 without early childhood caries ; age range 3-6 years) will be recruited for the study. Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded and saliva samples will be collected. Interleukin-32, Interleukin-10, Interleukin-6 and TNF-α will be analyzed in saliva samples by ELISA.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 3 Years 至 70 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children with untreated early chilhood caries
- •Age between 3 and 6 years
排除标准
- •Having a systemic problem or mental retardation
- •Children with treated caries
结局指标
主要结局
IL-32
时间窗: Baseline
Interleukin- 32 level
IL-10
时间窗: Baseline
Interleukin- 10 level
次要结局
- Tnf-Alpha(Baseline)
- IL-6(Baseline)
研究者
Sultan KELES
Assoc.Prof.Dr.
Aydin Adnan Menderes University
研究点 (1)
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