NL-OMON52118
Recruiting
Phase 4
The perioperative renal and metabolic outcomes after sodium-glucose cotransporter-2 inhibitor in cardiac surgery - an open-label phase IV randomized controlled trial - The MERCURI trial
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 80
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 to 90 years old (inclusive)
- •Undergoing elective cardiac surgery with cardio\-pulmonary bypass.
- •Providing informed consent
Exclusion Criteria
- •Current treatment with SGLT2 inhibitors.
- •Diabetes Mellitus Type 1
- •BMI\<25 for people with type 2 diabetes
- •Reduced renal function at baseline with eGFR\<30 ml/min.
- •Systolic blood pressure \< 100 mmHg at time of inclusion.
- •Emergency surgery, defined as in need of surgery for medical reasons \< 7
- •days, i.e. \*S1\-4\* according to the Amsterdam UMC classification.
- •Female of child\-bearing potential who is pregnant, breast\-feeding or intend
- •to become pregnant or is not using adequate contraceptive methods.
- •Known or suspected allergy to trial products or other drugs in the same
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Metabolic and renal outcomes in cardiac surgery patients receiving SGLT2 inhibitorsCardiac surgery associated acute kidney injuryNL-OMON26563Amsterdam UMC location AMC80
Completed
Not Applicable
The evaluation of postoperative renal function after new type plasma expanderPatients undergone operationJPRN-UMIN000017291Sapporo Medical University School of Medicine100
Completed
Not Applicable
Mechanisms of transiently impaired renal function during liver transplantatioiver transplantationUrological and Genital DiseasesSurgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedureISRCTN43452247Geneva University Hospitals (Hôpitaux Universitaires de Genève) (Switzerland)30
Not yet recruiting
Not Applicable
Intraoperative renal desaturation and postoperative acute kidney injury in patients undergoing robot-assisted laparoscopic radical prostatectomyprostate cancerJPRN-UMIN000053128Akita University30
Completed
Not Applicable
Preoperative renal function affects perioperative AKI and CKD in lower GI surgerygastrointestinal diseaseJPRN-UMIN000033608Department of Anesthesiology Kawasaki Municipal Tama Hospital500