Effects and adverse events of opioids: a study on the role of pharmacokinetic and pharmacogenetic heterogeneity.

Completed

• Conditions: kankerpijn; cancer pain; pain in cancer; 10027656

• Registration Number: NL-OMON33024
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1000

Inclusion Criteria

1.Hospitalized cancer patients with moderate or severe nociceptive pain treated with strong opioids.
2. Informed consent.

Exclusion Criteria

-

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Pain intensity, measured by Numeric Rating Scale<br /><br>Side effects of opioids: nausea/vomiting, dry mouth, somnolence, obstipation,<br /><br>myoclonus, confusion, hallucinations, sweating, measured by nurses on a<br /><br>4-points Likert Scale (none, slight, moderate, severe)<br /><br>Score on the Delirium Observation Screening Scale (DOS)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>