PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis

Completed

• Conditions: Hip Arthropathy; Regional Anesthesia Morbidity; Arthropathy of Hip
• Interventions: Procedure: Peripheral nerve blocks

• Registration Number: NCT05916209
• Lead Sponsor: Ospedale Edoardo Bassini

Brief Summary

Background: Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation. Fascia iliaca compartment block (FICB) has been recommended since it offers the best pain control with low risk of motor block. Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve (LFCN) block has been proposed as an effective alternative to FICB that offers similar pain control with a considerably lower risk of motor block. This study aimed to compare the afore mentioned blocks and determine which one yielded the lowest NRS score.

Detailed Description

This single-center, retrospective investigation was conducted at ASST Nord Milano Bassini hospital. The study was approved by the ethics committee "Comitato Etico Milano Area 3". The main outcome of the study was the comparison of postoperative pain at 6, 12 and 24 hours, expressed as NRS (numeric rating scale), between PENG and LCFN . Secondary outcomes included total opioid consumption expressed as milligrams of morphine equivalents (MME), time to first opioid request, time to first postoperative ambulation.

Study Timeline

• Study Start: 2023-02-01
• Primary Completion: 2023-03-01
• Study Completion: 2023-03-01
• Study First Submitted: 2023-05-19
• Status Verified: 2023-06
• Study First Submitted QC: 2023-06-13
• Last Update Submitted: 2023-06-13
• Study First Posted: 2023-06-23
• Last Update Posted: 2023-06-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• elective total hip replacement surgery for non-traumatic hip disease, age >18 years, complete clinical chart included the type of peripheral nerve block performed, signed consent form for spinal anesthesia and peripheral nerve block.

Exclusion Criteria

• incomplete chart, a peripheral nerve block other than PENG or FIC block was performed

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
PENG + LFCN Block	Peripheral nerve blocks	group in which PENG + LFCN Block was performed
FIC Block	Peripheral nerve blocks	group in which FIC Block was performed

Primary Outcome Measures

Name	Time	Method
pain control	24 hours after surgery	pain assessment with Numeric Rating Scale (NRS): a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"

Secondary Outcome Measures

Name	Time	Method
Morphine Milligram Equivalents (MME) of "pro re nata" (PRN) opioid doses	24 hours after surgery	we studied the effect of Regional anesthesia on opioid-sparing
MME of PRN opioid doses	12 hours after surgery	we studied the effect of Regional anesthesia on opioid-sparing

Trial Locations

Locations (1)

Ospedale Edoardo Bassini; 🇮🇹 Cinisello Balsamo, Milano, Italy