To assess frequency of Diffuse Large B Cell Lymphoma genetic subtypes in India
Not Applicable
- Conditions
- Health Condition 1: null- Denovo DLBCL cases registered at Tata Memorial Center from 2007 to 2013 will be screened. Out of these 350 cases will be enrolled based on availability of FFPEHealth Condition 2: D728- Other specified disorders of whiteblood cells
- Registration Number
- CTRI/2018/10/016107
- Lead Sponsor
- Duke Cancer Institute for Genome Science and Policy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Age >15 years
2 Denovo DLBCL cases who were treated in department of Medical Oncology
Exclusion Criteria
1.Non availability of formalin- fixed paraffin blocks
2.Non availability of Outcome Data
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Evaluating the frequency of GCB and ABC DLBCL subtypes with gene expression <br/ ><br>2. Comparison of frequency of DLBCL molecular subtypes (comparison of our data set with that of North America- Dr Daveâ??s lab data) <br/ ><br>3. RNA sequencing to identify DLBCL subtypes and its correlation with GEP subtypes profiling <br/ ><br>Timepoint: 3 years
- Secondary Outcome Measures
Name Time Method Effect of ABC and GCB subtypes on overall survivalTimepoint: 36 months