Pharmacokinetics of Curcumin in Healthy Volunteers
Not Applicable
Completed
- Conditions
- Healthy
- Registration Number
- NCT00181662
- Lead Sponsor
- Massachusetts General Hospital
- Brief Summary
This study looks to describe the pharmacokinetics of curcumin delivered as a single oral dose in healthy female volunteers. The impact of piperine and silybin on the pharmacokinetics of curcumin is also studied.
- Detailed Description
Healthy volunteers are seen on three separate visits and receive 4 gm of curcumin as a single oral dose either alone or with piperine or with silybin. Serial timed blood draws then are collected for pharmacokinetic analysis.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 6
Inclusion Criteria
- Healthy volunteer
- On no medications except for birth control pills
- Signed informed consent
Exclusion Criteria
- Pregnant
- Comorbid disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Curcumin pharmacology
- Secondary Outcome Measures
Name Time Method Interactions between piperine and curcumin Interactions between silybin and curcumin
Trial Locations
- Locations (1)
Massachusetts General Hospital
🇺🇸Boston, Massachusetts, United States