Comparative study of analgesic efficacy between phosphate codeine in combination with paracetamol and oxycodone hydrochloride, after extractions of impacted lower third molars.

Phase 4

• Conditions: postoperative pain; 13896

• Registration Number: RBR-8ntwmyq
• Lead Sponsor: niversidade Federal de Juiz de Fora

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-12-01
• Study Start: 2021-07-07
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patientes of both sexes; aged over 18; with similar dental impaction; absence of systemic diseases or locoregional changes; without contraindication to the use of dexamethasone, paracetamol, codeine phosphate or oxycodone; absence of a history of hypersensitivity to mepivacaine.

Exclusion Criteria

Patients with records containing insufficient or inadequately filled data; patients who did not return for the second extraction would be excluded from the final sample.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find that the dosage of 30mg of codeine phosphate in association with 500mg of paracetamol has highter analgesic efficacy than the dosage of 10mg of oxycodone after impacted lower third molar extractions.

Secondary Outcome Measures

Name	Time	Method
It is expected to find that the dosage of 30mg of codeine phosphate in combination with 500mg of acetaminophen is expected to have fewer side effects than a 10mg dosage of oxycodone after impacted lower third molar extractions.